In the human world, we can get away with saying “Pick on someone your own size”, but in the animal world, it’s fair game. If a predator can bring it down, no matter the size, they’ll go in for the chase. This is exactly the case when a pride of lions try and take down a huge giraffe.
someone I work with commented the other week that they had no idea how viscous Giraffe could be, always thinking they were peaceful (which I dare say they are mostly) i’d imagine the females can be even nastier in defence of the calfs !